There has been doping in sport throughout modern times, but before the steroid era athletes used different agents to enhance their performance. Learn about how strychnine use in the 1904 and 1908 Olympic marathons may have propelled runners to victory.
Episode 33: The Frozen Addicts
In 1983 patients began presenting with sudden onset Parkinsonian symptoms after using a new designer drug. Dr. Langston eventually was able to link the cases to exposure to the contaminant MPTP, and the future of Parkinson’s research was forever changed as a result.
Episode 32: Mining, Water, Rice, and Bone Pain
Rice, a staple food for a large portion of the world population, has been documented to have been cultivated, grown, and consumed for thousands of years. For those living around the Jinzu river in Toyama Prefecture in Japan in the early 1900s, rice and water consumption caused a pollution disease called “Itai-Itai disease”. Bone and…
Episode 31: Abortifacients, a Historical Perspective
Throughout history, women have sought to control their fertility with substances that “regulate” menstruation, terminate pregnancies, or induce labor. Teas, concoctions, and medicinal compounds containing pennyroyal, rue, artemsia, ergot, cohosh, quinine, and lead have caused significant toxicity and death when taken as abortifacients. In this talk we will explore the history of abortifacients from antiquity…
Episode 30: I’ve Been to Dwight
This is the story of Dr. Leslie Keeley and his gold cure elixir. His Keeley Institute in a small midwestern town was perhaps the most widely recognized alcohol treatment program in the United States in the 1890s. Although his elixir may have been no more than snake oil his treatment program foreshadowed treatment as we…
Episode 29: Laboratory X
State-sponsored poisoning and assassination is deeply ingrained in Russian politics. You’ve heard of Alexander Litvinenko, but where was the poison and delivery plan developed? And who were the other victims of Moscow’s poison laboratory?
Episode 28: A Stable Head with a Broken Heart
Drinkers asked for a bigger and more stable head and the brewers came up with a novel solution. The heaviest drinkers that couldn’t even afford a cup to pour their beer into and see a head started to mysteriously die of heart failure. An investigation begins!
Episode 27: The Thalidomide Tragedy and a Path to Safer Drugs
As one of the largest man made disasters in public health history, the discovery and realization of the disastrous effects of thalidomide in pregnant patients has paved a way to safe medication discovery and utilization. From this tragedy in modern medicine led new regulatory pathways, transparency in drug development, and expanded procedures to ensure therapeutic…
Episode 26: Botulinum Antitoxin
Our long history of attempting to find a treatment for botulism is a winding road of discovery, setbacks, and the constant challenge of balancing risk and benefit. Through major outbreaks that seized the nation’s attention and the disruption of major wars, however, the spirit of science and humanity prevailed, bringing us a therapy to help…
Episode 25: Beyond Bicycle Day: The Story of Albert Hofmann and the Discovery of LSDEpisode 25:
This talk will describe the early career of Albert Hofmann, his accidental discovery of the hallucinogenic properties of LSD-25, his legendary bicycle ride home from work during an LSD trip, and the legacy of his discovery.